Article
Clinical prediction of opioid use disorder in chronic pain patients: a cohort-retrospective study with a pharmacogenetic approach.
Minerva anestesiologica - 1 May 2024
Escorial Mónica, Muriel Javier, Agulló Laura, Zandonai Thomas, Margarit César, Morales Domingo, Peiró Ana M
Abstract excerpt
BACKGROUND: Opioids are widely used in chronic non-cancer pain (CNCP) management. However, they remain controversial due to serious risk of causing opioid use disorder (OUD). Our main aim was to develop a predictive model for future clinical translation that include pharmacogenetic markers. METHODS: An observational study was conducted in 806 pre-screened Spanish CNCP patients, under long-term use of opioids, to...
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