Article
Relation of aromatase gene polymorphism and hormone replacement therapy to serum estradiol levels, bone mineral density, and fracture risk in early postmenopausal women.
Annals of medicine - 1 Jan 2003
Salmen Timo, Heikkinen Anna-Mari, Mahonen Anitta, Kröger Heikki, Komulainen Marja, Pallonen Heli, Saarikoski Seppo, Honkanen Risto, Mäenpää Pekka H
Abstract excerpt
BACKGROUND: After the menopause, estrogen synthesis from androgens and androgen precursors by aromatase is the main source of circulating estrogens. AIM: To evaluate whether aromatase gene (CYP19)polymorphism affects circulating estradiol (E2) levels, bone mineral density (BMD), BMD change or fra...
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