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Article

Genetics of PICALM expression and Alzheimer's disease.

PloS one - 1 Jan 2014

Parikh Ishita, Fardo David W, Estus Steven

Abstract excerpt

Novel Alzheimer's disease (AD) risk factors have been identified by genome-wide association studies. Elucidating the mechanism underlying these factors is critical to the validation process and, by identifying rate-limiting steps in AD risk, may yield novel therapeutic targets. Here, we evaluated the association between the AD-associated polymorphism rs3851179 near PICALM, which encodes a clathrin-coated pit...

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Source

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Identifiers

PMID: 24618820
DOI: 10.1371/journal.pone.0091242
PMCID: PMC3949918

Genes

PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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