Genetic association of PICALM polymorphisms with Alzheimer's disease in Han Chinese.

doi:10.1016/j.jns.2010.09.027

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Article

Genetic association of PICALM polymorphisms with Alzheimer's disease in Han Chinese.

Journal of the neurological sciences - 15 Jan 2011

Yu Jin-Tai, Song Jing-Hui, Ma Teng, Zhang Wei, Yu Nan-Nan, Xuan Shi-Ying, Tan Lan

Abstract excerpt

PICALM might play an important role in AD pathology through participating in altering synaptic vesicle cycling or APP endocytosis. A recent genome-wide study (GWAS) identified a single nucleotide polymorphism (SNP) rs3851179 in the 5' to the PICALM gene strongly associated with Alzheimer's disease (AD) in Caucasians. In order to assess the involvement of the PICALM polymorphism in the risk of developing...

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Identifiers

PMID: 20951388
DOI: 10.1016/j.jns.2010.09.027

Genes

PICALM
APOE
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic association of PICALM polymorphisms with Alzheimer's disease in Han Chinese.PMID 20951388Read ↗

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Identification and confirmation of an exonic splicing enhancer variation in exon 5 of the Alzheimer disease associated PICALM gene.Semantic proximity Read ↗

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