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Article

Implication of a genetic variant at PICALM in Alzheimer’s disease patients and centenarians.

Journal of Alzheimer's disease : JAD - 1 Jan 2011

Piaceri Irene, Bagnoli Silvia, Lucenteforte Ersilia, Mancuso Michelangelo, Tedde Andrea, Siciliano Gabriele, Piacentini Silvia, Bracco Laura, Sorbi Sandro, Nacmias Benedetta

Abstract excerpt

A common polymorphism (rs3851179) in the PICALM (phosphatidylinositol-binding clathrin assembly protein) gene has been recently associated with reduced risk of developing late-onset Alzheimer’s disease (LOAD). We analyzed the genotype and allele distributions of the PICALM polymorphism in 813 Italian subjects, including LOAD patients and centenarians. The segregation of the PICALM rs3851179 showed no...

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Source

Identifiers

PMID: 21297266
DOI: 10.3233/JAD-2011-101791

Genes

PICALM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Implication of a genetic variant at PICALM in Alzheimer’s disease patients and centenarians.PMID 21297266Read ↗

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