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Article

Pharmacogenetics of microRNAs and microRNAs biogenesis machinery in pediatric acute lymphoblastic leukemia.

PloS one - 1 Jan 2014

López-López Elixabet, Gutiérrez-Camino Ángela, Piñán Maria Ángeles, Sánchez-Toledo José, Uriz Jose Javier, Ballesteros Javier, García-Miguel Purificación, Navajas Aurora, García-Orad África

Abstract excerpt

Despite the clinical success of acute lymphoblastic leukemia (ALL) therapy, toxicity is frequent. Therefore, it would be useful to identify predictors of adverse effects. In the last years, several studies have investigated the relationship between genetic variation and treatment-related toxicity. However, most of these studies are focused in coding regions. Nowadays, it is known that regions that do not codify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24614921
DOI: 10.1371/journal.pone.0091261
PMCID: PMC3948785

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DROSHA

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