Article
MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia.
Haematologica - 1 May 2011
Schotte Diana, De Menezes Renée X, Akbari Moqadam Farhad, Khankahdani Leila Mohammadi, Lange-Turenhout Ellen, Chen Caifu, Pieters Rob, Den Boer Monique L
Abstract excerpt
BACKGROUND: MicroRNA regulate the activity of protein-coding genes including those involved in hematopoietic cancers. The aim of the current study was to explore which microRNA are unique for seven different subtypes of pediatric acute lymphoblastic leukemia. DESIGN AND METHODS: Expression levels of 397 microRNA (including novel microRNA) were measured by quantitative real-time polymerase chain reaction in 81...
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