Article
Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in nulliparous women complicated with preeclampsia.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 May 2014
Chedraui Peter, Salazar-Pousada Danny, Villao Alejandro, Escobar Gustavo S, Ramirez Cecibel, Hidalgo Luis, Pérez-López Faustino R, Genazzani Andrea, Simoncini Tommaso
Abstract excerpt
OBJECTIVE: To determine the prevalence of C677T and A1298C Single-nucleotide polymorphisms (SNPs) of the MTHFR gene in nulliparous women complicated with preeclampsia (PE). METHODS: One hundred fifty gestations complicated with PE and their corresponding controls without the disease were recruited for the genotyping of C677T and A1298C polymorphisms of the MTHFR gene using restriction fragment length polymorphism...
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