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Article

Methylenetetrahydrofolate reductase polymorphism, folate, and susceptibility to preeclampsia.

Journal of the Society for Gynecologic Investigation - 1 Jan 2000

Powers R W, Minich L A, Lykins D L, Ness R B, Crombleholme W R, Roberts J M

Abstract excerpt

OBJECTIVES: To test the hypothesis that the common missense mutation of 5,10-methylenetetrahydrofolate reductase (MTHFR) (677 C to T, ala to val) is more prevalent among nulliparous preeclamptic women compared with control and transient hypertension of pregnancy patients. The correlation of the MTHFR T677/T677 genotype in mothers and fetuses was also investigated to test for possible maternal-fetal interactions....

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Source

Identifiers

PMID: 10205777
DOI: 10.1016/s1071-5576(98)00052-5

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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