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Article

Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in the placenta of pregnancies complicated with preeclampsia.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jul 2015

Chedraui Peter, Andrade Mariela E, Salazar-Pousada Danny, Escobar Gustavo S, Hidalgo Luis, Ramirez Cecibel, Spaanderman Marc E A, Kramer Boris W, Gavilanes Antonio W D

Abstract excerpt

BACKGROUND: Preeclampsia has been related to single-nucleotide polymorphisms (SNPs) of the methylenetetrahydrofolate reductase (MTHFR) gene; however, data regarding the placenta are still lacking. OBJECTIVE: To determine the frequency of C677T and A1298C SNPs of the MTHFR gene in the placenta of preeclamptic pregnancies and healthy controls. METHODS: Genotyping of C677T and A1298C polymorphisms of the MTHFR gene...

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Identifiers

PMID: 26036716
DOI: 10.3109/09513590.2015.1031104

Genes

MTHFR

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