Article
Association of DNA repair and cell cycle gene variations with breast cancer risk in Northeast Indian population: a multiple interaction analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2014
Wasson Mishi Kaushal, Chauhan Pradeep Singh, Singh L C, Katara Dheeraj, Dev Sharma Jagannath, Zomawia Eric, Kataki Amal, Kapur Sujala, Saxena Sunita
Abstract excerpt
Polymorphisms in DNA repair and cell cycle genes contribute to increased breast cancer (BC) risk. Their association and interaction in relation to betel quid and tobacco chewing habits need exhaustive multi-analytical investigation to explain BC predisposition due to DNA damage. Polymorphism in TP53-72Arg>Pro, RAD51-135G>C, BRCA2, and CCND1-G870A were examined in 204 BC cases and 217 controls from Northeast...
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