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Article

Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.

Scientific reports - 18 Jan 2017

Nagrani Rajini, Mhatre Sharayu, Rajaraman Preetha, Chatterjee Nilanjan, Akbari Mohammad R, Boffetta Paolo, Brennan Paul, Badwe Rajendra, Gupta Sudeep, Dikshit Rajesh

Abstract excerpt

To date, no studies have investigated the association of the GWAS-identified SNPs with BC risk in Indian population. We investigated the association of 30 previously reported and replicated BC susceptibility SNPs in 1,204 cases and 1,212 controls from a hospital based case-control study conducted at the Tata Memorial Hospital, Mumbai. As a measure of total susceptibility burden, the polygenic risk score (PRS) for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28098224
DOI: 10.1038/srep40963
PMCID: PMC5241870

Genes

CCND1
ESR1
FGFR2
UST

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