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Article

The interplay between XPG-Asp1104His polymorphism and reproductive risk factors elevates risk of breast cancer in Tanzanian women: A multiple interaction analysis.

Cancer medicine - 1 Jan 2023

Adolf Ismael C, Rweyemamu Linus P, Akan Gokce, Mselle Ted F, Dharsee Nazima, Namkinga Lucy A, Lyantagaye Sylvester L, Atalar Fatmahan

Abstract excerpt

BACKGROUND: Reproductive history and genetics are well-known risk factors of breast cancer (BC). Little is known about how these factors interact to effect BC. This study investigated the association of ten polymorphisms in DNA repair genes with BC susceptibility in the Tanzanian samples and further analyzed the association between reproductive risk factors and disease risk METHODS: A hospital-based case-control...

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PMID: 35691022
DOI: 10.1002/cam4.4914
PMCID: PMC9844639

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