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Article

A pilot study evaluating genetic alterations that drive tobacco- and betel quid-associated oral cancer in Northeast India.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2014

Yadav Dhirendra Singh, Chattopadhyay Indranil, Verma Anand, Devi Thoudam Regina, Singh L C, Sharma Jagannath Dev, Kataki Amal Ch, Saxena Sunita, Kapur Sujala

Abstract excerpt

The susceptibility of an individual to oral cancer is mediated by genetic factors and carcinogen-exposure behaviors such as betel quid chewing, tobacco use, and alcohol consumption. This pilot study was aimed to identify the genetic alteration in 100 bp upstream and downstream flanking regions in addition to the exonic regions of 169 cancer-associated genes by using Next Generation sequencing with aim to...

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Identifiers

PMID: 24943687
DOI: 10.1007/s13277-014-2222-4

Genes

APC
BARD1
BRCA1
BRMS1
ADH6
ATM
BRCA2
CCND2
EGFR
FGFR4
FLNC
GAS1
HRAS
MSH6
NBL1
RASSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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