Article
Cortical ¹¹C-PIB uptake is associated with age, APOE genotype, and gender in "healthy aging".
Journal of Alzheimer's disease : JAD - 1 Jan 2014
Scheinin Noora M, Wikman Kristina, Jula Antti, Perola Markus, Vahlberg Tero, Rokka Johanna, Någren Kjell, Viitanen Matti, Rinne Juha O
Abstract excerpt
BACKGROUND/OBJECTIVE: Our aim was to elucidate factors that contribute to amyloid-β (Aβ) accumulation in the brains of the seemingly healthy elderly population, and whether there is interplay between those factors. METHODS: We conducted a cross-sectional positron emission tomography (PET) study with the amyloid tracer 11C-PIB, in 64 cognitively healthy subjects (54-89 years). In addition to PET, magnetic...
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