Article
Independent and Interactive Influences of the APOE Genotype and Beta-Amyloid Burden on Cognitive Function in Mild Cognitive Impairment.
Journal of Korean medical science - 1 Feb 2016
Seo Eun Hyun, Kim Sang Hoon, Park Sang Hag, Kang Seong-Ho, Choo Il Han
Abstract excerpt
This study aimed to investigate the independent and interactive influences of apolipoprotein E (APOE) ε4 and beta-amyloid (Aβ) on multiple cognitive domains in a large group of cognitively normal (CN) individuals and patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Participants were included if clinical and cognitive assessments, amyloid imaging, and APOE genotype were all available...
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