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Article

18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons.

Neurobiology of aging - 1 Sept 2014

Knopman David S, Jack Clifford R, Wiste Heather J, Lundt Emily S, Weigand Stephen D, Vemuri Prashanthi, Lowe Val J, Kantarci Kejal, Gunter Jeffrey L, Senjem Matthew L, Mielke Michelle M, Roberts Rosebud O, Boeve Bradley F, Petersen Ronald C

Abstract excerpt

Our objective was to examine associations between glucose metabolism, as measured by (18)F-fluorodeoxyglucose positron emission tomography (FDG PET), and age and to evaluate the impact of carriage of an apolipoprotein E (APOE) ε4 allele on glucose metabolism and on the associations between glucose metabolism and age. We studied 806 cognitively normal (CN) and 70 amyloid-imaging-positive cognitively impaired...

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Identifiers

PMID: 24702820
DOI: 10.1016/j.neurobiolaging.2014.03.006
PMCID: PMC4053507

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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