Article
Triggering receptor expressed on myeloid cells 2 variants are rare in Parkinson's disease in a Han Chinese cohort.
Neurobiology of aging - 1 Jul 2014
Feng Shu-jun, Nie Kun, Gan Rong, Huang Jing, Zhang You-wen, Wang Li-min, Zhao Jie-hao, Tang Hong-mei, Gao Liang, Zhu Rui-ming, Duan Zhen-peng, Zhang Yu-hu, Wang Li-juan
Abstract excerpt
Recent studies have reported that a rare nonsynonymous variant rs75932628-T in the TREM2 gene is associated with increased risk of Alzheimer's disease and Parkinson's disease (PD) in European-descended populations. However, the association between rare TREM2 mutations and PD risk remains unknown in Chinese population. We directly sequenced exon2 of TREM2 in a cohort of 476 PD patients and 432 healthy controls...
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