Article
Assessment of TREM2 rs75932628 association with amyotrophic lateral sclerosis in a Chinese population.
Journal of the neurological sciences - 15 Aug 2015
Chen Xueping, Chen Yongping, Wei Qianqian, Guo Xiaoyan, Cao Bei, Ou Ruwei, Zhao Bi, Shang Hui-Fang
Abstract excerpt
Although, rs75932628 in triggering receptor expressed on myeloid cells 2 (TREM2) was shown to increase the risk for Alzheimer's disease, there is no agreement on the association between this variant and the risk for amyotrophic lateral sclerosis (ALS). We conducted a large-sample study to investigate if this variant is associated with ALS in a Chinese population. A total of 868 sporadic ALS (SALS) and 869 healthy...
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