Article
Genetic analysis of TREM2 variants in Chinese Han patients with sporadic Parkinson's disease.
Neuroscience letters - 26 Jan 2016
Tan Ting, Song Zhi, Yuan Lamei, Xiong Wei, Deng Xiong, Ni Bin, Chen Yong, Deng Hao
Abstract excerpt
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease and is characterized by the degeneration of dopaminergic neurons in substantia nigra. Recently, rs75932628 (p.R47H) of the triggering receptor expressed on myeloid cells 2 gene (TREM2) was identified to be associated with PD in American, Spanish, Irish, and Polish population. To explore whether TREM2 variants...
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