Article
Association study of TREM2 polymorphism rs75932628 with leucoaraiosis or Parkinson's disease in the Han Chinese population.
BMJ open - 12 Jan 2016
Li Zhiming, Zhong Li, Gu Long, Huang Wenqing, Shi Xinzhen, Zhang Xilin, An Xingkai, Lin Qing, Tzeng Chi-Meng
Abstract excerpt
OBJECTIVES: The previously reported functional mutation rs75932628-T (p.R47H) in the triggering receptor expressed on myeloid cells 2 (TREM2) is a genetic risk factor for Alzheimer's disease, Parkinson's disease (PD) and frontotemporal dementia, in European populations. This study aims to assess the genetic association of the variant rs75932628-T with PD and leucoaraiosis (LA) in a Han Chinese population....
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