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Article

Targeting TREM2 for Parkinson's Disease: Where to Go?

Frontiers in immunology - 1 Jan 2021

Li Xiao-Xian, Zhang Feng

Abstract excerpt

Parkinson's disease (PD) is one of most common neurodegenerative disorders caused by a combination of environmental and genetic risk factors. Currently, numerous population genetic studies have shown that polymorphisms in myeloid cell-triggered receptor II (TREM2) are associated with a variety of neurodegenerative disorders. Recently, TREM2 has been verified to represent a promising candidate gene for PD...

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Identifiers

PMID: 35003116
DOI: 10.3389/fimmu.2021.795036
PMCID: PMC8740229

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