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Extracellular matrix dynamics in development and regenerative medicine

23 Jan 2008

Abstract excerpt

The extracellular matrix (ECM) regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. Far from being a static structure, the ECM is constantly undergoing remodeling--i.e. assembly and degradation--particularly during the normal processes of development, differentiation and wound repair. When misregulated, this can contribute to disease. ECM assembly is regulated...

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PMID: 18216330
DOI: 10.1242/jcs.006064

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