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Role of Extracellular Matrix in Development and Cancer Progression

4 Oct 2018

Abstract excerpt

The immense diversity of extracellular matrix (ECM) proteins confers distinct biochemical and biophysical properties that influence cell phenotype. The ECM is highly dynamic as it is constantly deposited, remodelled, and degraded during development until maturity to maintain tissue homeostasis. The ECM's composition and organization are spatiotemporally regulated to control cell behaviour and differentiation, but...

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PMID: 30287763
DOI: 10.3390/ijms19103028

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