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Article

Variations in the MHC region confer risk to esophageal squamous cell carcinoma on the subjects from high-incidence area in northern China.

PloS one - 1 Jan 2014

Shen Fang-Fang, Yue Wen-Bin, Zhou Fu-You, Pan Ying, Zhao Xue-Ke, Jin Yan, Song Xin, Li Bei, Han Xue-Na, Tang Sa, Li Yan, Yuan Guo, Chen Li-Sha, Liu Ya-Li, Hu Yan-Long, Li Xiu-Min, Ren Jing-Li, Wang Li-Dong

Abstract excerpt

BACKGROUND: The human major histocompatibility complex (MHC) is the most important region in vertebrate genome, and is crucial in innate immunity. Recent studies have demonstrated the possible role of polymorphisms in the MHC region to high risk for esophageal squamous cell carcinoma (ESCC). Our previous genome-wide association study (GWAS) has indicated that the MHC region may confer important risk loci for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24595008
DOI: 10.1371/journal.pone.0090438
PMCID: PMC3942432

Genes

TRIM27

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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