Article
Barrett associated MHC and FOXF1 variants also increase esophageal carcinoma risk.
International journal of cancer - 1 Oct 2013
Dura Polat, van Veen Elke M, Salomon Jody, te Morsche Rene H M, Roelofs Hennie M J, Kristinsson Jon O, Wobbes Theo, Witteman Ben J M, Tan Adriaan C I T L, Drenth Joost P H, Peters Wilbert H M
Abstract excerpt
Barrett's esophagus, with gastroesophageal reflux disease and obesity as risk factors, predisposes to esophageal adenocarcinoma (EAC). Recently a British genome wide association study identified two Barrett's esophagus susceptibility loci mapping within the major histocompatibility complex (MHC; rs9257809) and closely to the Forkhead-F1 (FOXF1; rs9936833) coding gene. An interesting issue is whether polymorphisms...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
