Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel genetic locus at MHC region for esophageal squamous cell carcinoma in Chinese populations.

PloS one - 1 Jan 2017

Zhang Peng, Li Xin-Min, Zhao Xue-Ke, Song Xin, Yuan Ling, Shen Fang-Fang, Fan Zong-Min, Wang Li-Dong

Abstract excerpt

BACKGROUND: Our previous genome-wide association study (GWAS) identified three independent single nucleotide polymorphisms (SNPs) in human major histocompatibility complex (MHC) region showing association with esophageal squamous cell carcinoma (ESCC). In this study, we increased GWAS sample size on MHC region and performed validation in an independent ESCC cases and normal controls with aim to find additional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

Share to Genetic Loci

Share to Linkage Disequilibrium

Share to Major Histocompatibility Complex

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 28493959
DOI: 10.1371/journal.pone.0177494
PMCID: PMC5426749

Genes

SCAND3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel genetic locus at MHC region for esophageal squamous cell carcinoma in Chinese populations.PMID 28493959Read ↗

Variations in the MHC region confer risk to esophageal squamous cell carcinoma on the subjects from high-incidence area in northern China.Semantic proximity Read ↗

Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations.Semantic proximity Read ↗

Candidate gene association study of esophageal squamous cell carcinoma in a high-risk region in Iran.Semantic proximity Read ↗

Candidate susceptibility variants for esophageal squamous cell carcinoma.Semantic proximity Read ↗

Barrett associated MHC and FOXF1 variants also increase esophageal carcinoma risk.Semantic proximity Read ↗

Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.Semantic proximity Read ↗

Genetic variants in the HLA class II region associated with risk of cutaneous squamous cell carcinoma.Semantic proximity Read ↗

High expression of HLA-DQA1 predicts poor outcome in patients with esophageal squamous cell carcinoma in Northern ChinaSemantic proximity Read ↗

Genetic variants at 4q21, 4q23 and 12q24 are associated with esophageal squamous cell carcinoma risk in a Chinese population.Semantic proximity Read ↗

Copy number loss of variation_91720 in PIK3CA predicts risk of esophageal squamous cell carcinoma.Semantic proximity Read ↗

Epigenetic alterations of a novel antioxidant gene SLC22A3 predispose susceptible individuals to increased risk of esophageal cancerSemantic proximity Read ↗

Genetic variants at 8q24 are associated with risk of esophageal squamous cell carcinoma in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.