Article
Link between CIITA rs3087456 polymorphism and the risk of laryngeal squamous cell carcinoma in a Chinese population.
Pathology, research and practice - 1 Jan 2020
Xue Yi, Tang Di, Li Sheng-Jie, Zhou Jian, Hsueh Chi-Yao, Zhao Dan-Dan, Heng Yu, Tao Lei, Lu Li-Ming
Abstract excerpt
The class II trans-activator (CIITA) is the master regulator of the major histocompatibility complex (MHC) gene expression. CIITA mutations have been previously associated with several kinds of tumors, while the role of CIITA polymorphisms (rs3087456) in laryngeal squamous cell carcinoma (LSCC) is little known. We evaluate the link between CIITA polymorphisms and the existence of LSCC in patients. This study was...
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