Article
Dynamics of MutS-mismatched DNA complexes are predictive of their repair phenotypes.
Biochemistry - 1 Apr 2014
DeRocco Vanessa C, Sass Lauryn E, Qiu Ruoyi, Weninger Keith R, Erie Dorothy A
Abstract excerpt
MutS recognizes base-base mismatches and base insertions/deletions (IDLs) in newly replicated DNA. Specific interactions between MutS and these errors trigger a cascade of protein-protein interactions that ultimately lead to their repair. The inability to explain why different DNA errors are repa...
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