Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Requirement for Phe36 for DNA binding and mismatch repair by Escherichia coli MutS protein.

Nucleic acids research - 15 Sept 2000

Yamamoto A, Schofield M J, Biswas I, Hsieh P

Abstract excerpt

The MutS family of DNA repair proteins recognizes base pair mismatches and insertion/deletion mismatches and targets them for repair in a strand-specific manner. Photocrosslinking and mutational studies previously identified a highly conserved Phe residue at the N-terminus of Thermus aquaticus MutS protein that is critical for mismatch recognition in vitro. Here, a mutant Escherichia coli MutS protein harboring a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Adenosine Triphosphate
Share to Alanine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Pair Mismatch

Share to Escherichia coli Proteins

Share to Hydrolysis

Share to MutS DNA Mismatch-Binding Protein

Share to Phenylalanine

Source

Open in PubMed Open full text

Identifiers

PMID: 10982877
DOI: 10.1093/nar/28.18.3564
PMCID: PMC110738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirement for Phe36 for DNA binding and mismatch repair by Escherichia coli MutS protein.PMID 10982877Read ↗

Identification and Characterization of a Thermostable MutS Homolog from Thermus aquaticusSemantic proximity Read ↗

The MutS C terminus is essential for mismatch repair activity in vivo.Semantic proximity Read ↗

The alternating ATPase domains of MutS control DNA mismatch repair.Semantic proximity Read ↗

Analysis of the mismatch and insertion/deletion binding properties of Thermus thermophilus, HB8, MutS.Semantic proximity Read ↗

Nuclease activity of the MutS homologue MutS2 from Thermus thermophilus is confined to the Smr domain.Semantic proximity Read ↗

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch.Semantic proximity Read ↗

Dynamics of MutS-mismatched DNA complexes are predictive of their repair phenotypes.Semantic proximity Read ↗

Mechanism of MutS searching for DNA mismatches and signaling repair.Semantic proximity Read ↗

Heteroduplex DNA and ATP induced conformational changes of a MutS mismatch repair protein from Thermus aquaticus.Semantic proximity Read ↗

Direct observation of three conformations of MutS protein regulated by adenine nucleotides.Semantic proximity Read ↗

Construction and purification of his6-Thermus thermophilus MutS protein.Semantic proximity Read ↗

Directly fishing out subtle mutations in genomic DNA with histidine-tagged Thermus thermophilus MutS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.