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Article

Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.

PloS one - 1 Jan 2017

Lee Hsiang-Lin, Cheng Hsin-Lin, Liu Yu-Fan, Chou Ming-Chih, Yang Shun-Fa, Chou Ying-Erh

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. Human WW domain-containing oxidoreductase (WWOX) gene has been identified as a tumor suppressor gene in multiple cancers. We hypothesize that genetic variations in WWOX are associated with HCC risk. METHODOLOGY/PRINCIPAL FINDINGS: Five single-nucleotide polymorphisms (SNPs) of the WWOX gene were evaluated from 708...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28426730
DOI: 10.1371/journal.pone.0176141
PMCID: PMC5398630

Genes

WWOX

Provenance

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