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Article

Genetic association study identifies a functional CNV in the WWOX gene contributes to the risk of intracranial aneurysms.

Oncotarget - 29 Mar 2016

Fan Jin, Sun Wen, Lin Min, Yu Ke, Wang Jian, Duan Dan, Zheng Bo, Yang Zhenghui, Wang Qingsong

Abstract excerpt

Intracranial aneurysms (IAs) accounts for 85% of hemorrhagic stroke. Genetic factors have been known to play an important role in the development of IAs. A functional CNV (CNV-67048) of human WW domain-containing oxidoreductase (WWOX), which has been identified as a tumor suppressor gene in multiple cancers, was identified to be associated with gliomas risk previously. Here, we hypothesized that the CNV-67048...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26910372
DOI: 10.18632/oncotarget.7546
PMCID: PMC4941300

Genes

WWOX

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Source receipt: pubmed, retrieved 7 Sept 2026.

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