Bridging Integrator 1 (BIN1) Genotype Effects on Working Memory, Hippocampal Volume, and Functional Connectivity in Young Healthy Individuals.

doi:10.1038/npp.2015.30

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Article

Bridging Integrator 1 (BIN1) Genotype Effects on Working Memory, Hippocampal Volume, and Functional Connectivity in Young Healthy Individuals.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2015

Zhang Xiaolong, Yu Jin-Tai, Li Jin, Wang Chao, Tan Lan, Liu Bing, Jiang Tianzi

Abstract excerpt

Alzheimer's disease (AD) is the most common form of dementia and exhibits a considerable level of heritability. The bridging integrator 1 (BIN1) gene has recently been identified in several large genome-wide association studies (GWAS) as the second most important risk locus for AD following apolipoprotein E (APOE). However, how and when the established genetic risk locus BIN1 rs744373 confers risk to late-onset...

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Identifiers

PMID: 25630570
DOI: 10.1038/npp.2015.30
PMCID: PMC4915264

Genes

BIN1
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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