Article
Alpha-synuclein repeat variants and survival in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2014
Chung Sun Ju, Biernacka Joanna M, Armasu Sebastian M, Anderson Kari, Frigerio Roberta, Aasly Jan O, Annesi Grazia, Bentivoglio Anna Rita, Brighina Laura, Chartier-Harlin Marie-Christine, Goldwurm Stefano, Hadjigeorgiou Georgios, Jasinska-Myga Barbara, Jeon Beom Seok, Kim Yun Joong, Krüger Rejko, Lesage Suzanne, Markopoulou Katerina, Mellick George, Morrison Karen E, Puschmann Andreas, Tan Eng-King, Crosiers David, Theuns Jessie, Van Broeckhoven Christine, Wirdefeldt Karin, Wszolek Zbigniew K, Elbaz Alexis, Maraganore Demetrius M
Abstract excerpt
OBJECTIVES: To determine whether α-synuclein dinucleotide repeat (REP1) genotypes are associated with survival in Parkinson's disease (PD). METHODS: Investigators from the Genetic Epidemiology of Parkinson's Disease Consortium provided REP1 genotypes and baseline and follow-up clinical data for cases. The primary outcome was time to death. Cox proportional hazards regression models were used to assess the...
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