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Article

Unique phenotype of human tonsillar and in vitro-induced FOXP3+CD8+ T cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2009

Siegmund Kerstin, Rückert Beate, Ouaked Nadia, Bürgler Simone, Speiser Andreas, Akdis Cezmi A, Schmidt-Weber Carsten B

Abstract excerpt

Forkhead box p3 (FOXP3) is known to program the acquisition of suppressive capacities in CD4(+) regulatory T cells (Treg), whereas its role in CD8(+) T cells is unknown. The current study investigates whether FOXP3 also acts as a Treg master switch in peripheral blood and tonsillar CD8(+) T cells...

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Source

Identifiers

PMID: 19201865
DOI: 10.4049/jimmunol.0802271

Genes

FOXP3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19201865-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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