Article
Tissue-resident regulatory T cells accumulate at human barrier lymphoid organs.
Immunology and cell biology - 1 Sept 2021
Hewavisenti Rehana V, Ferguson Angela L, Gasparini Georgia, Ohashi Tomoki, Braun Asolina, Watkins Thomas S, Miles John J, Elliott Michael, Sierro Frederic, Feng Carl G, Britton Warwick J, Gebhardt Thomas, Tangye Stuart, Palendira Umaimainthan
Abstract excerpt
Regulatory T cells (Tregs) play a critical role in immune regulation and peripheral tolerance. While different types of Tregs have been identified in both mice and humans, much of our understanding about how these cells maintain immune homeostasis is derived from animal models. In this study, we examined two distinct human lymphoid organs to understand how repeated exposure to infections at the mucosal surface...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.