Article
Genetic variations within metalloproteinases impact on the prophylaxis of depressive phases in bipolar patients.
Neuropsychobiology - 1 Jan 2014
Drago Antonio, Monti Barbara, De Ronchi Diana, Serretti Alessandro
Abstract excerpt
BACKGROUND: The genetic background of the antidepressant response to pharmacological treatment in bipolar disorder (BD) remains elusive. This issue is of primary relevance in that the depressive phases of BD are difficult to treat and they are associated with suicide. AIM: We investigated the role of a set of genetic variations (single-nucleotide polymorphisms) harbored by matrix metalloproteinases (MMPs) as...
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