Article
Matrix metalloproteinase-9 gene and bipolar mood disorder.
Neuromolecular medicine - 1 Jan 2009
Rybakowski Janusz K, Skibinska Maria, Leszczynska-Rodziewicz Anna, Kaczmarek Leszek, Hauser Joanna
Abstract excerpt
Matrix metalloproteinase-9 (MMP-9) plays a role in many pathological conditions (e.g., cancer and heart disease). Recently, MMP-9 has been implicated in various aspects of brain functions (e.g., neuroplasticity and epileptogenesis) and thus, we hypothesized that MMP-9 gene may be associated with bipolar mood disorder. The study was performed on 416 patients with bipolar mood disorder, including 75 patients with...
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