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Article

Association between genetic variation in the myo-inositol monophosphatase 2 (IMPA2) gene and age at onset of bipolar disorder.

Journal of affective disorders - 1 May 2018

Tomioka Yoko, Jiménez Esther, Salagre Estela, Arias Bárbara, Mitjans Marina, Ruiz Victoria, Sáiz Pilar, García-Portilla María Paz, de la Fuente Lorena, Gomes-da-Costa Susana Patricia, Bobes Julio, Vieta Eduard, Benabarre Antoni, Grande Iria

Abstract excerpt

INTRODUCTION: The age at onset of bipolar disorder (BD) has significant implications for severity, duration of affective episodes, response to treatment, and psychiatric comorbidities. It has been suggested that early-onset BD (EO-BD) could represent a clinically distinct subtype with probable genetic risk factors different from those of late-onset BD (LO-BD). To date, several genes have been associated with BD...

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Identifiers

PMID: 29499505
DOI: 10.1016/j.jad.2018.02.002

Genes

IMPA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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