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Article

Association between Sirtuin 1 Gene rs10997870 Polymorphism and Suicide Behaviors in Bipolar Disorder.

Neuropsychobiology - 1 Jan 2016

Nivoli Alessandra, Porcelli Stefano, Albani Diego, Forloni Gianluigi, Fusco Federica, Colom Francesc, Vieta Eduard, Serretti Alessandro

Abstract excerpt

BACKGROUND/AIMS: Suicidal behavior (SB) in bipolar disorder (BD) is a complex multifactorial event resulting from an interaction of genetic, neurobiological and psychosocial factors. Recent studies identified new possible mechanisms, suggesting a role for sirtuins (SIRTs 1-7), a family of nicotinamide adenine dinucleotide-dependent enzymes with a multifaceted role in the central nervous system. The aims of the...

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PMID: 27424200
DOI: 10.1159/000446921

Genes

SIRT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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