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Article

A haplotype of glycogen synthase kinase 3β is associated with early onset of unipolar major depression.

Genes, brain, and behavior - 1 Oct 2010

Saus E, Soria V, Escaramís G, Crespo J M, Valero J, Gutiérrez-Zotes A, Martorell L, Vilella E, Menchón J M, Estivill X, Gratacòs M, Urretavizcaya M

Abstract excerpt

Recent findings suggest that glycogen synthase kinase 3β (GSK3β) may play a role in the pathophysiology and treatment of mood disorders. Various genetic studies have shown the association of GSK3β polymorphisms with different mood disorder phenotypes. We hypothesized that genetic variants in the GSK3β gene could partially underlie the susceptibility to mood disorders. We performed a genetic case-control study of...

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Identifiers

PMID: 20618448
DOI: 10.1111/j.1601-183X.2010.00617.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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