Article
The oncoprotein v-Myb activates transcription of Gremlin 2 during in vitro differentiation of the chicken neural crest to melanoblasts.
Gene - 25 Apr 2014
Starostová Michaela, Cermák Vladimír, Dvořáková Marta, Karafiát Vít, Kosla Jan, Dvořák Michal
Abstract excerpt
The neural crest (NC) is a transient dynamic structure of ectodermal origin, found in early vertebrate embryos. The multipotential NC cells migrate along well defined routes, differentiate to various cell types including melanocytes and participate in the formation of various permanent tissues. As there is only limited information about the molecular mechanisms controlling early events in melanocyte specification...
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