Article
A novel model to study the dorsolateral migration of melanoblasts.
Mechanisms of development - 1 Dec 1999
Beauvais-Jouneau A, Pla P, Bernex F, Dufour S, Salamero J, Fässler R, Panthier J J, Thiery J P, Larue L
Abstract excerpt
Melanocytes derived from pluripotent neural crest cells migrate initially in the dorsolateral pathway between the ectoderm and dermomyotome. To understand the role of specific proteins involved in this cell migration, we looked for a cellular model that mimics the in vivo behavior of melanoblasts, and that allows functional studies of their migration. We report here that wild-type embryonic stem (ES) cells are...
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