Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate.

Development (Cambridge, England) - 1 Sept 1999

Lister J A, Robertson C P, Lepage T, Johnson S L, Raible D W

Abstract excerpt

We report the isolation and identification of a new mutation affecting pigment cell fate in the zebrafish neural crest. Homozygous nacre (nac(w2)) mutants lack melanophores throughout development but have increased numbers of iridophores. The non-crest-derived retinal pigment epithelium is normal, suggesting that the mutation does not affect pigment synthesis per se. Expression of early melanoblast markers is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Terminator
Share to Helix-Loop-Helix Motifs

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leucine Zippers

Share to Melanophores

Share to Microphthalmia-Associated Transcription Factor

Share to Neural Crest

Share to Pigment Epithelium of Eye

Share to Zebrafish Proteins

Source

Identifiers

PMID: 10433906
DOI: 10.1242/dev.126.17.3757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate.PMID 10433906Read ↗

Duplicate mitf genes in zebrafish: complementary expression and conservation of melanogenic potential.Semantic proximity Read ↗

Melanophore sublineage-specific requirement for zebrafish touchtone during neural crest development.Semantic proximity Read ↗

The Tomita collection of medaka pigmentation mutants as a resource for understanding neural crest cell development.Semantic proximity Read ↗

Microphthalmia transcription factor induces both retinal pigmented epithelium and neural crest melanocytes from neuroretina cells.Semantic proximity Read ↗

Touchtone promotes survival of embryonic melanophores in zebrafish.Semantic proximity Read ↗

Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently.Semantic proximity Read ↗

Zebrafish pigmentation mutations and the processes of neural crest development.Semantic proximity Read ↗

Identification of kit-ligand a as the Gene Responsible for the Medaka Pigment Cell Mutant few melanophore.Semantic proximity Read ↗

Identification of <i>kit-ligand a</i> as the Gene Responsible for the Medaka Pigment Cell Mutant <i>few melanophore</i>Semantic proximity Read ↗

Dominant Negative Mitf Allele Impacts Melanophore and Xanthophore Development and Reveals Collaborative Interactions With Tfec in Zebrafish Chromatophore Lineages.Semantic proximity Read ↗

Interplay between Foxd3 and Mitf regulates cell fate plasticity in the zebrafish neural crest.Semantic proximity Read ↗

How the zebrafish gets its stripes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.