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Article

Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage.

Genes & development - 15 Jul 2000

Goding C R

Abstract excerpt

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Topics

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Share to DNA-Binding Proteins
Share to Gene Expression Regulation, Developmental
Share to Melanocytes
Share to Melanoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microphthalmia-Associated Transcription Factor

Share to Models, Biological

Share to Neural Crest

Share to Transcription, Genetic

Source

Identifiers

PMID: 10898786

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

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Research trail→

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Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage.PMID 10898786Read ↗

MITF: master regulator of melanocyte development and melanoma oncogene.Semantic proximity Read ↗

Beyond MITF: Multiple transcription factors directly regulate the cellular phenotype in melanocytes and melanoma.Semantic proximity Read ↗

Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation.Semantic proximity Read ↗

MITF: a stream flowing for pigment cells.Semantic proximity Read ↗

MITF, the Janus transcription factor of melanoma.Semantic proximity Read ↗

Stem Cell-Derived Models of Neural Crest Are Essential to Understand Melanoma Progression and Therapy ResistanceSemantic proximity Read ↗

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.Semantic proximity Read ↗

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.Semantic proximity Read ↗

Genomic analysis of the Microphthalmia locus and identification of the MITF-J/Mitf-J isoform.Semantic proximity Read ↗

Loss of MITF activity leads to emergent cell states from the melanocyte stem cell lineageSemantic proximity Read ↗

“Transcription physiology” of pigment formation in melanocytes: central role of MITFSemantic proximity Read ↗

How Neural Crest Transcription Factors Contribute to Melanoma Heterogeneity, Cellular Plasticity, and Treatment Resistance.Semantic proximity Read ↗

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