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Article

Complementation of melanocyte development in SOX10 mutant neural crest using lineage-directed gene transfer.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2004

Hou Ling, Loftus Stacie K, Incao Arturo, Chen Amy, Pavan William J

Abstract excerpt

An in vitro gene complementation approach has been developed to dissect gene function and regulation in neural crest (NC) development and disease. The approach uses the avian RCAS virus to express genes in NC cells derived from transgenic mice expressing the RCAS receptor TVA, under the control of defined promoter elements. Constructs for creating TVA transgenic mice were developed using site-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14699577
DOI: 10.1002/dvdy.10468

Genes

SOX10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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