Article
Pmel17 expression is Mitf-dependent and reveals cranial melanoblast migration during murine development.
Gene expression patterns : GEP - 1 Dec 2003
Baxter Laura L, Pavan William J
Abstract excerpt
In situ hybridization (ISH) analysis of the murine melanosomal gene, Pmel17, demonstrated robust expression in the presumptive retinal pigmented epithelium (RPE) starting at E9.5, and in neural crest-derived melanoblasts starting at E10.5. Pmel17 expression is not detectable in embryos mutated for Microphthalmia-associated transcription factor (Mitf), demonstrating transcriptional dependence of Pmel17 on Mitf in...
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