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Article

Cell-autonomous and cell non-autonomous signaling through endothelin receptor B during melanocyte development.

Development (Cambridge, England) - 1 Jul 2004

Hou Ling, Pavan William J, Shin Myung K, Arnheiter Heinz

Abstract excerpt

The endothelin receptor B gene (Ednrb) encodes a G-protein-coupled receptor that is expressed in a variety of cell types and is specifically required for the development of neural crest-derived melanocytes and enteric ganglia. In humans, mutations in this gene are associated with Waardenburg-Shah syndrome, a disorder characterized by pigmentation defects, deafness and megacolon. To address the question of whether...

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Source

Identifiers

PMID: 15201217
DOI: 10.1242/dev.01193

Genes

KIT
EDNRA
EDNRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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