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Article

High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment.

Journal of virology - 1 Sept 2014

Wu Nicholas C, Young Arthur P, Al-Mawsawi Laith Q, Olson C Anders, Feng Jun, Qi Hangfei, Luan Harding H, Li Xinmin, Wu Ting-Ting, Sun Ren

Abstract excerpt

UNLABELLED: Viral proteins often display several functions which require multiple assays to dissect their genetic basis. Here, we describe a systematic approach to screen for loss-of-function mutations that confer a fitness disadvantage under a specified growth condition. Our methodology was achi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24965464
DOI: 10.1128/JVI.01494-14
PMCID: PMC4136320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24965464-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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