Article
Influenza Viruses Control the Vertebrate Type I Interferon System: Factors, Mechanisms, and Consequences
26 Aug 2009
Abstract excerpt
Virus research of the past decades showed that the vertebrate type I interferon (IFN) system is in principle capable of slowing down the replication and spread of most if not all viruses at early stages of infection. However, influenza viruses and other viral pathogens have evolved gene products to subvert this innate defense to enable efficient reproduction and thereby cause disease. Inhibition of type I IFN...
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